分离分析新材料与新技术分离分析新材料与新技术
团队名称：分离分析新材料与新技术
团队成员：邓启良，张晨曦，王小聪、李沁然
2）高灵敏、高通量分离分析检测技术
3）新型高灵敏传感检测
4）无机功能分子材料
5）导电功能高分子纳米材料的自组装
研究成果：
近三年发表代表性论文(2012-2015)：
1. Kejin Sun, Qiliang Deng, Ting Guo, Rina Su, Yuchen Gu and Shuo Wang High selectivity and sensitivity fluorescent sensing melamine based on the combination of fluorescent chemosensor with molecularly imprinted polymers，RSC Advances 2015
2. Cuicui Liu, Qiliang Deng, Guozhen Fang, Xuan Huang, Shuo Wang, and Jinsong He A Novel Poly(ionic liquid) Interface-Free Two-Dimensional Monolithic Material for the Separation of Multiple Types of Glycoproteins. ACS Appl. Mater. Interfaces, 2015, 7 (36), pp 20430–20437
3. Ting Guo, QiliangDeng, GuozhenFang, CuicuiLiu, XuanHuang, ShuoWang Molecularly imprinted upconversion nanoparticles for highly selective and sensitive sensing of Cytochrome c Biosensors and Bioelectronics 74 (2015) 498–503
4. Huilin Liu, Guozhen Fang, Qiliang Deng, Shuo Wang A triple-dimensional sensing chip for discrimination of eight antioxidants based on quantum dots and grapheme Biosensors and Bioelectronics Volume 74 ( 2015) Pages 313–317
5.Jinxiang Liu, Qiliang Deng, Dingyin Tao, Kaiguang Yang, Lihua Zhang, Zhen Liang, Yukui Zhang Preparation of protein imprinted materials by hierarchical imprinting techniques and application in selective depletion of albumin from human serum. Scientific Reports, DOI: 10.1038/srep05487.
6. Cuicui Liu, Qiliang Deng, Guozhen Fang, Xue Feng, Hailong Qian, Shuo Wang Facile preparation of organic-inorganic hybrid polymeric ionic liquid monolithic column with a one-pot process for protein separation in capillary electrochromatography Anal Bioanal Chem 2014 406(28):7175-7183
7. Cuicui Liu, Qiliang Deng, Guozhen Fang, Xuan Huang and Shuo Wang, Facile synthesis of graphene doped poly(ionic liquid) boronate affinity material for specific capture of glycoproteins, J. Mater. Chem. B, 2014, 2, 5229-5237.
8. Shifang Yuan, Qiliang Deng, Guozhen Fang Jianhua Wu Wangwang Li Shuo Wang Protein imprinted ionic liquid polymer on the surface of multiwall carbon nanotubes with high binding capacity for lysozyme Journal of Chromatography B 2014, 960, 239-246.
9. Guozhen Fang, Hailong Qian, Qiliang Deng, Xuqin Ran, Yukun Yang, Cuicui Liua and Shuo Wang, A novel C18 reversed phase organic–silica hybrid cationic monolithic capillary column with an ionic liquid as an organic monomer via a “one-pot” approach for capillary electrochromatography RSC Adv., 2014, 4, 15518-15525
10. Qiliang Deng, Jianhua Wu, Yang Chen, Zhijun Zhang, Yang Wang, Guozhen Fang, Shuo Wang and Yukui Zhang Guanidinium Functionalized Superparamagnetic Silica Spheres for Selective Enrichment of Phosphopeptides and Intact Phosphoproteins from Complex Mixtures J. Mater. Chem. B, 2014, 2, 1048
11.Cui-Cui Liu, Qi-Liang Deng, Guo-Zhen Fang, Hui-Lin Liu, Jian-Hua Wu, Ming-Fei Pan, Shuo Wang, Ionic liquids monolithic columns for protein separation in capillaryelectrochromatography, Analytica Chimica Acta 2013, 804, 313-320.
12. Qiliang Deng, Jianhua Wu, Xiaorui Zhai, Guozhen Fang Shuo Wang, Highly Selective Fluorescent Sensing of Proteins Based on a Fluorescent Molecularly Imprinted Nanosensor, Sensors 2013, 13, 12994-13004.
13. Wangwang Li, Qiliang Deng, Guozhen Fang, Yang Chen, Jie Zhan and Shuo Wang, Facile synthesis of Fe3O4@TiO2-ZrO2 and its application in phosphopeptide enrichment, J. Mater. Chem. B, 2013, 1, 1947-1961.
14.Guozhen Fang, Wei Gao, Qiliang Deng, Kun Qian, Haitao Han, Shuo Wang Highly selective capture of phosphopeptides using a nano titanium dioxide-multiwalled carbon nanotube nanocomposite. Analytical Biochemistry 2012, 423, 210-217.
15. Guozhen Fang, Xiaorui Zhai, Qiliang Deng, Shifang Yuan, Meirong Cao and Shuo Wang Preparation and Evaluation of Lysozyme Molecularly Imprinted Polymer Film on the Surface of Multi-wall Carbon Nanotubes Current Organic Chemistry, 2012, 16, 1461-1467
16. Qiliang Deng, Yanli Li, Jianhua Wu, Yang Liu, Guozhen Fang, Shuo Wang and Yukui Zhang Highly sensitive fluorescent sensing for water based on poly(m-aminobenzoic acid) Chem. Commun., 2012, 48, 3009–3011
17. Yu Wang, Qiliang Deng, Guozhen Fang, M ingfei Pan, Yang Yu, Shuo Wang, A novel ionic liquid monolithic column and its separation properties in capillary electrochromatography Anal. Chim. Acta 712 (2012) 1-8. （封面文章）
18.Shifang Yuan, Qiliang Deng, Guozhen Fang, Mingfei Pan, Xiaorui Zhai and Shuo Wang A novel ionic liquid polymer material with high binding capacity for proteins J. Mater. Chem., 2012, 22, 3965–3972
19. Cuicui Liu, Guozhen Fang, Qiliang Deng, Yan Zhang, Jingjing Feng, Shuo Wang Determination of metolcarb in food by capillary electrophoresis immunoassay with a laser-induced fluorescence detector ELECTROPHORESIS 2012, 33(9-10), 1471-1476.
20. Chen-Xi Zhang, Hai-Wen Chen, Wen-Min Wang, YuYing Zhang, Syntheses, crystal structures and magnetic properties of two new Ln(III)-nitronyl nitroxide (Ln="Gd(III)," Dy(III)) complexes, Inorg. Chem.Commun.24, 177–180, 2012
23. Chen-Xi Zhang, Wen-Min Wang, Xiang-Yu Zhao, YuYing Zhang, Syntheses, crystal structures, magnetic properties of two new lanthanide-nitronyl nitroxide complexes (Ln(III) = Gd-III, Nd-III), Polyhedron. 30, 3177–3181, 2011.
24. Ya-Qiu Sun, Dong-Zhao Gao, Yan-Yan Xu, Guo-Ying Zhang, Lan-Lan Fan, Cheng-Peng Li, Tong-Liang Hu, Dai-Zheng Liao, Chen-Xi Zhang, Coordination polymers of macrocyclic oxamide with 1,3,5-benzenetricarboxylate: syntheses, crystal structures and magnetic properties, Dalton Trans., 40, 5528-5537, 2011.
25. Kai zhang, Xiao-Qin Zhang, Chen-Xi Zhang, Shu-Juan Zhang, Xiao-Cong Wang, Dong-Lan Sun, Electrochromic behavior of NiO-TiO2 films prepared with sodium dodecyl sulfonate added to the sol, Sol. Energ. Mat.Sol.C, 114, 192-198, 2013.
26. Chen-Xi Zhang, Xue-Mei Qiao, Yu-Kun Kong, Two Lanthanide-nitronyl nitroxide radicals compounds with slow magnetic relaxation behavior, J.Mol.Struc., 1081, 348-354, 2015.
27. Xue-Mei Qiao, Chen-Xi Zhang, Yu-Kun Kong, Two Mononuclear Tri-Spin Compounds based on the Lanthanide-Nitronyl Nitroxide Radicals: Synthesis, Crystal Structure, and Magnetic Properties, Z. Anorg. Allg. Chem., 640, 1684-1687, 2014.
28.Yu-Kun Kong, Xue-Hui Lv, Xiang-Lan Wang, Chen-Xi Zhang, Qing-Lun Wan, Two cobalt complexes containing different nitronyl nitroxide radicals: Structure and magnetic properties, Inorg. Chem.Commun. 60, 91–94, 2015.
29. Xiaocong Wang, Jing Liu, Shujuan Zhang, Du Chimin, Flexible conductive polyaniline-silica/polypropylene composite membrane, Synthetic Metals，2012，162：1459– 1463.
30. Xiangzheng Hu, Xiaocong Wang *, Jing Liu, Shujuan Zhang, Xiu He, Fabrication of mesoporous dendritic silica nanofibers by using dendritic polyaniline templates, Materials Chemistry and Physics，2012，137：17-21.
31. Qinran Li, Kaiguang Yang, Yu Liang, Bo Jiang, Jianxi Liu, Lihua Zhang, Zhen Liang, Yukui Zhang, Surface protein imprinted core-shell particles for high selective lysozyme recognition prepared by reversible addition fragmentation chain transfer strategy [J]. ACS Appl. Mater. Interfaces, 2014, 6, 21954-21960.
32. Qinran Li, Kaiguang Yang, Jinxiang Liu, Lihua Zhang, Zhen Liang, Yukui Zhang, Transferrin recognition based on a protein imprinted material prepared by hierarchical imprinting technique [J]. Microchim. Acta., 2013, 180, 1379-1386.
33. Qinran Li, Kaiguang Yang, Senwu Li, Lukuan Liu, Jianxi Liu, Lihua Zhang, Zhen Liang, Yukui Zhang, Preparation of surface imprinted core-shell particles via a metal chelating strategy: specific recognition of porcine serum albumin[J]. Microchim. Acta., Accepted. DOI:10.?1007/?s00604-015-1640-3.
科研项目：
主持在研及已完成国家级科研课题：
国家自然科学基金：
新型聚离子液毛细管整体柱制备及其对蛋白分离机理研究，项目编号：21375094，负责人：邓启良教授
新型蛋白质分子印迹固相萃取材料制备与应用，项目编号 21075089，负责人：邓启良教授
蛋白质分子印迹技术用于蛋白质组学的探索，项目编号 20605024，负责人：邓启良教授
氮氧自由基-金属单链分子磁体和合成及其磁性质的研究，项目编号20771081，负责人：张晨曦教授
科技部“十二五”国家科技计划课题
食品蛋白中非法添加物及有害污染物的检测和评价技术研究，项目编号：2013AA102202，负责人：邓启良教授
粮食中霉菌毒素高选择富集检测技术，项目编号：2012AA101609-2，负责人：邓启良教授
主持企业横向课题：润滑油添加剂的制备及应用，天津市舜能润滑油股份有限公司项目，负责人：张晨曦教授
近三年申请及授权专利：
王硕;邓启良;王俊平;汪羽，一种新型离子液体毛细管整体柱的制备方法，ZL201110326287.3
邓启良，陈洋，王硕，利用荧光增强法检测二、三价铁离子的方法申请号：CN201410487940
王硕;邓启良;王俊平;郭婷，一种上转换蛋白识别材料的制备方法，申请号：CN201505326287.3
王硕;邓启良;王俊平;郭婷，高选择荧光传感蛋白材料制备及其对蛋白识别：申请号：CN2015064567.0
王硕;邓启良;王俊平;方国臻;袁士芳, 一种吸附多种蛋白质的离子液体聚合物材料的制备方法, CN201110325899.0
邓启良，陈洋，利用荧光增强法检测二、三价铁离子的方法申请号：CN201410487940
王硕;邓启良;王俊平;郭婷，一种上转换蛋白识别材料的制备方法，申请号：CN201505326287.3
王硕;邓启良;王俊平;郭婷，高选择荧光传感蛋白材料制备及其对蛋白识别：申请号：CN2015064567.0
王硕;邓启良;王俊平;方国臻;袁士芳, 一种吸附多种蛋白质的离子液体聚合物材料的制备方法, CN201110325899.0
邓启良，顾雨辰，一种用于磷酸肽富集的聚胍基离子液体材料的制备方法，申请号：CN201510591262.4
邓启良，苏日娜，一种聚季铵盐离子液体酶反应器的制备方法，申请号：CN201510519264.X
荣誉奖励：